Jessica Shepard scored a career-high 39 points and No. 2 Notre Dame withstood a 3-point barrage by DePaul for a 91-82 victory Sunday.
Shepard, who twice scored 35 points for Nebraska before transferring, hit 17 of 22 shots and had 11 rebounds.
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Arike Ogunbowale added 21 for the Irish (10-1). She had just two points at halftime while making one of nine shots.
DePaul (7-4) shot 13-for-36 on 3s. Ashton Millender led the Blue Demons with 18 points.
Shepard scored 26 points as Notre Dame led 41-40 at halftime. The Irish were up 60-58 Irish after three quarters.
Notre Dame’s Jackie Young missed her first five shots while adjusting to a mask to protect a broken nose sustained Friday in practice. She finished with just four points.
Marina Mabrey had 13 points and Kathryn Westbeld had 10 points for Notre Dame.
Amarah Coleman had 17 and Chante Stonewall 16 points for DePaul.