Titans (10-1) at Lions (0-11)
Time: 11:30 a.m.; WBBM-Ch. 2.
Line: Titans by 11.
Weather: Dome.
Titans: Four days after first loss, Titans get chance to erase memory. Sticking to basics will get it done against generous defense.
Lions: Well, Lions finally sold out game — because it’s Thanksgiving. Unless Daunte Culpepper suddenly starts making big plays, hard to see upset.
Fantasy outlook: Rookie Chris Johnson should improve 4.5-yard rushing average and 5 rushing TDs against NFL’s worst rushing defense. Lions rookie Calvin Johnson has 8 TD catches, including at least 1 in 6 of last 7 games.
Injuries: Lions going without starting defensive ends Jared DeVries (hand, out for season) and Dewayne White (calf).
Prediction: Titans 28, Lions 10.
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Seahawks (2-9) at Cowboys (7-4)
Time: 3:15 p.m.; WFLD-Ch. 32, WSCR-AM 670.
Line: Cowboys by 12 1/2.
Weather: 30 percent chance of rain, 75 degrees.
Seahawks: Julius Jones gets start at RB against team that gave up on him. That’s about all drama that’s left in Seattle’s lost season.
Cowboys: After midseason slump as Tony Romo’s injured finger healed and Terrell Owens got hot — 213 receiving yards last week — Cowboys warming up for run at playoffs. Seahawks present no roadblock.
Fantasy outlook: Jones has rushed for 637 yards and 2 TDs. In 2 games since returning from finger injury, Romo has completed 63.6 percent for 539 yards with 4 TD passes and 2 INTs.
Injuries: Cowboys guard Kyle Kosier (foot) is out.
Prediction: Cowboys 27, Seahawks 13.
Cardinals (7-4) at Eagles (5-5-1)
Time: 7:15 p.m.; NFL Network, WSCR-AM 670.
Line: Eagles by 3.
Weather: Partly cloudy, 40 degrees.
Cardinals: Kurt Warner is 37 but trend line is heading back up. Cardinals take first division title since ’75 with victory. Cross-country travel on three days’ rest and No. 30 running game are issues.
Eagles: Donovan McNabb was benched during Sunday’s loss to Ravens but will start. Still, trend line is heading down. Eagles only 22-21-1 with McNabb starting last four years.
Fantasy outlook: Anquan Boldin leads NFL with 11 TD receptions, averaging 12.0 per catch. Eagles rookie DeSean Jackson has 47 catches, only 1 TD.
Injuries: Eagles running backs Brian Westbrook (knee, ankle) and Correll Buckhalter (knee) both questionable.
Prediction: Eagles 21, Cardinals 20.