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Fans of NBC’s “Will & Grace” have heard Megan Mullally’s Karen refer to her acquaintance “Candy Bergen” on several occasions, but on Thursday, that enigmatic friend will finally appear, played by none other than Candace Bergen herself. The episode finds Karen and Jack (Sean Hayes) out celebrating Jack’s first month as a student nurse. An encounter with Bergen, Karen’s nemesis, leads to a prank war.

Since “Murphy Brown” ended in 1998, Bergen has appeared only sparingly in network series offerings. She did multiple episodes on HBO’s “Sex and the City” and lent her voice to two episodes of Fox’s “The Family Guy.”

During her 10-year stint as the eponymous newswoman on “Murphy Brown,” Bergen was nominated for seven Emmys, winning five. More recent credits for the actress, who earned an Oscar nomination for 1979’s “Starting Over,” include the features “The In-Laws,” “Sweet Home Alabama,” “Miss Congeniality” and “View From the Top.”

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Edited by Cara DiPasquale ([email protected]) and Victoria Rodriguez ([email protected])